To open the Lead Researcher’s Office puzzle box in Resident Evil Requiem, get Corrosive from the East Wing Conference Room, use it on the box’s padlock, then enter Star → Sun → Moon → Sun. The box contains the Sun Quartz and a Leatherbound Notebook.
Where to find the puzzle box
The box is in the Lead Researcher’s Office on the second floor of the Care Center’s East Wing. You need Corrosive before you can open it; pick it up in the Conference Room along the East Wing corridor. PowerPyx’s all-puzzles guide identifies the location and prerequisite.
How to open the box
- Go to the Conference Room in the East Wing and collect Corrosive.
- In the Lead Researcher’s Office, use Corrosive on the puzzle box’s padlock.
- Enter Star → Sun → Moon → Sun.
- Take the Sun Quartz and Leatherbound Notebook from the box.
The office photographs provide the in-game clue to the sequence. If you prefer to enter it directly, the button positions are Star (right), Sun (left), and Moon (middle), as described in PC Gamer’s February 27, 2026 guide.
Quick Recap
Rank #4
- Grace Ashcroft, an FBI intelligence analyst who is introverted and easily scared, representing a new type of character for the Resident Evil series. Grace will experience horror from the same perspective as the player as she learns to overcome her fears throughout the course of the story.
- For the first time ever in Resident Evil history, players will be able to freely switch between both first- and third-person perspectives throughout the game.
- An Anniversary to Remember: With March 2026 marking the Resident Evil series’ 30-year anniversary, Resident Evil Requiem marks its own milestone in the franchise.
Rank #3
- DELUXE EDITION CONTENT — Includes the full game plus five costumes, four weapon skins, two screen filters, two charms, the Raccoon City Classic Audio Pack, and Letters from 1998.
- A NEW ERA OF SURVIVAL HORROR — Experience the ninth mainline Resident Evil adventure, blending terrifying survival horror with pulse-pounding action in an immersive new chapter.
- TWO INTERTWINED JOURNEYS — Experience the story through FBI analyst Grace Ashcroft and legendary agent Leon S. Kennedy, each bringing a distinct gameplay style to the nightmare.
- SURVIVE AS GRACE ASHCROFT — Step into terrifying survival horror as FBI analyst Grace Ashcroft faces deadly threats and fights to escape death.
- TAKE ACTION AS LEON S. KENNEDY — Dive into pulse-pounding action with legendary agent Leon S. Kennedy as the two protagonists’ journeys collide.
Rank #2
- A NEW ERA OF SURVIVAL HORROR — Experience the ninth mainline Resident Evil adventure, blending terrifying survival horror with pulse-pounding action in an immersive new chapter.
- TWO INTERTWINED JOURNEYS — Experience the story through FBI analyst Grace Ashcroft and legendary agent Leon S. Kennedy, each bringing a distinct gameplay style to the nightmare.
- SURVIVE AS GRACE ASHCROFT — Step into terrifying survival horror as FBI analyst Grace Ashcroft faces deadly threats and fights to escape death.
- TAKE ACTION AS LEON S. KENNEDY — Dive into pulse-pounding action with legendary agent Leon S. Kennedy as the two protagonists’ journeys collide.
- RETURN TO RESIDENT EVIL — Enter the latest mainline chapter of Capcom’s iconic survival horror series for a chilling experience built around fear, tension, and action.
#1 Best Overall
- Amazon Exclusive - 2 sided poster included in every game!
- Grace Ashcroft, an FBI intelligence analyst who is introverted and easily scared, representing a new type of character for the Resident Evil series. Grace will experience horror from the same perspective as the player as she learns to overcome her fears throughout the course of the story.
- For the first time ever in Resident Evil history, players will be able to freely switch between both first- and third-person perspectives throughout the game.
- An Anniversary to Remember: With March 2026 marking the Resident Evil series’ 30-year anniversary, Resident Evil Requiem marks its own milestone in the franchise.
- Pre-orders for Resident Evil Requiem are now open, with the bonus of Grace’s costume: Apocalypse. Please note that the picture weapon does not come with the costume, but it can be obtained in-game.
What the box rewards are for
- Sun Quartz: Use it with the other Quartz pieces at the Central Hall door to progress.
- Leatherbound Notebook: It contains instructions for opening the Organ Transport Box. PowerPyx’s Care Center walkthrough confirms the box contents and the notebook’s purpose.
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